NCS with severe aortic stenosis: increased periop events, but without death in 30 patient series

Case series from the Mayo Clinic in ScottsdaleĀ in Am J CardiolĀ (time to quote somebody else besides Toronto and Rotterdam)

We studied 30 patients with asymptomatic, severe AS with a mean age of 78 + or – 9 years, an aortic valve area of 0.77 + or – 0.16 cm(2), a mean gradient of 50.1 + or – 9.5 mm Hg, and a peak gradient of 84 + or – 22 mm Hg. They were compared to 60 age-matched (within 2 years) and gender-matched (ratio of 1:2) patients with mild-to-moderate AS (controls).

Combined postoperative events were more common for the patients (n = 10; 33%) than for the controls (n = 14; 23%), but the difference was not statistically significant (p = 0.06).

Intraoperative hypotension requiring vasopressor use was more likely for the patients (n = 9; 30%) than for the controls (n = 10; 17%; odds ratio 2.5; p = 0.11).

The perioperative myocardial infarction rates were similar for both groups (3%; p = 0.74). No deaths, heart failure events, or ventricular arrhythmias occurred in the patients and 1 death and 1 ventricular arrhythmia episode occurred in the controls

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